Douglas S. Stanley, M.D., Inc.

Internal Medicine

7780 North Fresno Street, Suite 102
Fresno, California 93720
Ph (559) 447-9027
Fx (559) 447-1675

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Dr. Stanley's Notes

Stay current on the latest health news! Learn more about medical treatments, advances in technology, seasonal health issues and more!

PPI's (Prilosec, Prevacid, Protonic, Nexium, Aciphex) and Risk of Dementia:  2/17/16

I have received some calls and emails pertaining to the recent information concerning the relationship between the use of PPI's (Proton Pump Inhibitors) and the developement of dementia.  This is based on a recent study published in the Feb. 15 journal JAMA Neurology which showed that individuals over age 75 who are regular users of PPI's (Defined by at least 1 presciption filled every 3 months) had a 44% increased risk of dementia, compared with seniors not using the drugs.  The study only found an assoicciation and not a cause and effect link.  You have to be careful with this manner of interpretation.  The majority of patients on PPI's are overweight, are more likely to eat an unhealthy diet, drink alcohol in excess, smoke as well as many other potential risks.  This study did not contol for diet and body weight as risk factors and both of these are risk factors for developing cognitive decline and demetia later in life.   The bottom line is if you do not need to be on the medication you shouldn't be taking the medication.  If you are on it and would like to stop go ahead a discontinue it.  If you have symptoms consistently at a frequency of 2-3 times a week without it, you need to be on a daily PPI or else your risk of bleeding ulcers, erosion of the esophagus and, ultimately esophageal cancer, increase substantially.  It should also be noted that similar findings occured with the use of H2 blockers (Zantac, Pecid and Tagamet).  All medications have benefits as well as side effects.  It is my job to present the pluses and minuses to your medication regimen.  I don not want you taking something that you do not need.  Stay healthy and have fun!!


Douglas Shane Stanley, M.D.


EXERCISE:  Now that the weather is starting to cool down, there is no excuse for not exercising.  I recommend NOT making it a big program because that only makes an excuse for not having the time to do it.  Start out slow.  A 15 minute walk 3 x a day.  Squats or wall squats.  Jumping jacks, Push ups.  Hell, kicking a can!!!!  I do not care what it is but it is time to start.  I have been recommending the Scientific Seven Minute Workout to many of my "too busy to exercise" patients.  It is a free app for your smart phone or Ipad that has you do 12 simple exercises for 30 seconds each and a 10 second rest in between.  It is equivalent to jogging 30 minutes.  Only do what you can but it is a great start.  I am sad to say that if you exercise 20 minutes a day, 3 days a week (That is an hour a week!!!!) you will be considered the top 10% of active Americans above age 35!!!!!  Scary to know we are that sedentary as a country.  Let's change that.  I know you all can be in that top 10%.


THANK YOU!!!:  I would like to give a big thank you to Gloria M. for reminding me that this website was out of date and I need to utilize it more.  Please feel free to ask me any questions and I would be happy to answer them for all of you to read.  I will try to post at least a few things a week to keep you well informed.

Thank you for reading!!

Dr. Stanley  



Routine vaccinations are recommended by the medical societies and insurances but most are not covered.  These include TdaP (Tetanus and Whooping cough) which should be boosted every 10 years.  Pneumonia vaccine at least before age 65 and a booster after age 65 or every 6 years if you have a chronic respiratory problem such as asthma and COPD.  Shingles (Zostavax) one time vaccination after age 60.  Please contact your insurance providers to determine if they are covered.  I strongly recommend staying up to date on your vaccinations but realize that you may be billed for them.  My staff and I will make you aware of this prior to giving a vaccination.

Last Updated Friday, February 28, 2020 - 06:10 PM.

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